| 摘要: |
| 目的 了解抗菌药物临床应用专项整治以来，我国医院的抗菌药物使用情况。方法 2011年和2012年分别选取了241所医院进行调查。运用系统随机抽样方法抽取5—9月期间医院的门诊处方和住院病历进行分析。抗菌药物使用强度（每百人天DDDs值）、门诊患者抗菌药物处方比例、综合I类切口手术预防使用抗菌药物比例等为主要分析指标。结果 从2011年至2012年，被调查医院的平均抗菌药物使用强度和综合I类切口手术预防使用抗菌药物比例下降有统计学意义；门诊患者抗菌药物处方使用率整体变化不显著，联合用药情况仍普遍存在。且医院的规模与抗菌药物使用存在显著关联性。结论 仍需通过进一步加强抗生素耐药性监测以及对医务工作者和公众抗菌药物使用培训等管理措施，从本质上改善抗菌药物使用情况。 |
| 关键词: 抗菌药物临床应用 抗菌药物使用强度 抗菌药物预防使用 |
| DOI： |
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| 基金项目: |
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| Investigation and Analysis of Antibiotic Stewardship Program in China |
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| Abstract: |
Objective To assess the implementation of the special antibiotic stewardship program in hospitals in China (2011-2012) from antibiotic stewardship program. Methods There were 241 hospitals selected in 2011 and 2012, respectively. A systematic random sampling strategy was employed to select outpatient prescriptions and inpatients medication orders (with or without type I incision operations). Data were collected with regards to the usage of antibiotics, the usage rate of outpatient prescriptions and the antibiotic use for surgical prophylaxis on type I incisions. Results The usage rate of outpatient prescriptions and the antibiotic use for surgical prophylaxis on type I incisions decreased. There was statistic meaning. The changes of the usage rate of outpatient prescriptions weren’t significant. There was significant correlation between hospital scale and antibiotic use. Conclusion Antibiotic usage should be improved through strengthening antibiotic resistance monitoring and training antibiotic use of medical staff and the public. |
| Key words: clinical usage of antibiotics,antibiotic usage amount, antibiotic prophylaxisusage |
